| Indication | Examples | Initial therapy | SatO2 target |
| Critical patients | Polytrauma Shock | Mask with reservoir bag at 15 lpm | 94% - 98% |
| ARF type I | Asthma Pulmonary embolism Pulmonary edema Pneumonia | Nasal cannula at 2 - 4 lpm or Facial mask at 5 - 10 lpm | 94% - 98% |
| ARF type II | COPD Bronchiectasis Obesity Sleep apnea Neuromuscular diseases | Nasal cannula at 2 - 4 lpm or Facial mask at 5 - 10 lpm | 88% - 92% |
| Special situations | Carbon monoxide poisoning pneumothorax | Mask with reservoir bag at 15 lpm | 94% - 98% |